检验医学与临床2016，Vol.13Issue(17)：2412-2413,2416,3.DOI:10.3969/j.issn.1672-9455.2016.17.002
2型糖尿病并发冠心病患者血清游离脂肪酸及超敏CRP水平的分析
Analysis on serum concentrations of FFA and hs-CRP for T2DM patients complicated with CHD
摘要
Abstract
Objective To investigate the correlation between serum free fatty acid (FFA) and high sensitive C reactive protein (hs‐CRP) levels in patients with type 2 diabetes mellitus(T2DM ) complicated with coronary heart disease(CHD) .Methods 80 T2DM+CHD patients treated in the hospital from January 2011 to December 2014 were enrolled in the study ,and 80 patients with T2DM alone were also recruited during the same period as control .Serum levels of glucose(FPG) ,total cholesterol (TG) ,total cho‐lesterol(CRP) ,total cholesterol(TC) ,hs‐CRP and FFA were measured in the two groups of patients .According to the degree of vascular stenosis in patients with CHD+ T2DM ,patients were divided into two groups ,single vascular disease(SVD) and multiple vascular disease(MVD)group .Compare the difference of the above 5 indicators in patients with different severity ,and use Logistic regression to analyze the correlation between those indicators and CHD .Results The levels of FFA ,TC ,TG ,hs‐CRP and FPG in T2DM+CHD group were higher than those in T2DM group(P<0 .01) .The levels of FPG ,TC ,TG ,hs‐CRP and FFA in MVD group were higher than those in group SVD(P<0 .01) .Logistic analysis showed that hs‐CRP and FFA were related factors for T2DM+CHD(P<0 .05) .Conclusion FFA and hs‐CRP levels were related with the development of CHD in T2DM patients which the clinical treatment needs to focus on .关键词
游离脂肪酸/超敏C反应蛋白/2型糖尿病/冠心病Key words
free fatty acids/high-sensitive C reactive protein/type 2 diabetes/coronary heart disease引用本文复制引用
陈立侠,孙玉真,李兴达..2型糖尿病并发冠心病患者血清游离脂肪酸及超敏CRP水平的分析[J].检验医学与临床,2016,13(17):2412-2413,2416,3.基金项目
国家高技术研究发展计划（“863”计划）资助项目（2014AA022304）。 （）
