摘要
Abstract
Objective To investigate the curative effect of vascular interventional therapy combined with splenectomy for hyper‐splenism in patients with liver cirrhosis .Methods 100 patients with liver cirrhosis complicated with hypersplenism in the hospital from June 2014 to June 2015 were enrolled in the study ,and divided into observation group and the control group according to ran‐dom number table method .The observation group were treated with vascular intervention therapy combined with splenectomy ,while the control group were treated with only splenectomy .The changes of indicators in routine blood test such as white blood cells (WBC) ,platelets(PLT) ,and IgG ,IgA ,IgM concentrations were observed after treatment .Clinical efficacy and the incidence of com‐plications were compared between the two groups .Results After treatment ,the levels of PLT and WBC in the two groups both in‐creased ,and the levels of PLT and WBC in the observation group were higher than those in the control group ,the levels of IgM ,IgA and IgG in the observation group were higher than those in control group ,the differences were all statistically significant(P<0 .05) .The total effective rate in observation group was 96 .00% (48/50) ,which was higher than that in control group[74 .00% (37/50)];the incidence of complications was 18 .00% (9/50) which was lower than that of the control group [50 .00% (25/50)];in the observation group ,the body temperature ,fever duration ,pain score and pain duration were lower than those in the control group;the differences were all significant(P<0 .05) .Conclusion Vascular intervention combined with splenectomy has obvious curative effect in the treatment of liver cirrhosis ,which could reduce complications after surgery and is worthy of clinical application .关键词
脾切除术/肝硬化/脾亢进Key words
splenectomia/hepatocirrhosis/hypersplenism
