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胰激肽原酶联合甲钴胺片治疗糖尿病视网膜病变患者视野缺损的疗效研究

曹奎 何春梅 邹强性

检验医学与临床2016,Vol.13Issue(17):2474-2475,2478,3.
检验医学与临床2016,Vol.13Issue(17):2474-2475,2478,3.DOI:10.3969/j.issn.1672-9455.2016.17.026

胰激肽原酶联合甲钴胺片治疗糖尿病视网膜病变患者视野缺损的疗效研究

The effect of pancreatic kininogenase combined with methylcobalamin in the treatment of visual field defect for patients with diabetic retinopathy

曹奎 1何春梅 1邹强性1

作者信息

  • 1. 四川省绵阳万江眼科医院眼科 621000
  • 折叠

摘要

Abstract

Objective To investigate the effect of pancreatic kininogenase combined with methylcobalamin in the treatment of visual field defect for patients with diabetic retinopathy .Methods 80 patients with non‐proliferative diabetic retinopathy who were treated in the hospital were enrolled in the study ,and randomly divided into observation and control group equally .Patients in Con‐trol group were treated with pancreatic kininogenase ,while patients in the observation group were treated with methylcobalamin tablets in addition to pancreatic kininogenase .After 5 months′ treatment ,the effect of the two therapies were compared .Bleeding spot count ,blood vessel tumor volume ,visual field intensity ,macular thickness were used as indicators .Results The condition of patients in the two groups significantly improved and the effective rate of the observation group was 97 .5% ,which was higher than 80 .0% in the control group ,the difference was statistically significant(P<0 .05) .After treatment ,bleeding spot count ,blood vessel tumor volume ,visual field intensity changed in both observation and control group ,and the differences were statistically significant (P<0 .05) .Indicators such as bleeding spot count ,blood vessel tumor volume and visual field intensity in observation group were better than that in control group with statistically significant difference(P<0 .05) .Conclusion The pancreatic kininogenase therapy combined with methylcobalamin treatment significantly improved the clinical symptoms and could be extensively applied in clinic .

关键词

胰激肽原酶/甲钴胺/糖尿病视网膜病变/视野缺损/临床疗效

Key words

pancreatic kininogenase/methylcobalamin/diabetic retinopathy/visual field defect/clinical curative effect

引用本文复制引用

曹奎,何春梅,邹强性..胰激肽原酶联合甲钴胺片治疗糖尿病视网膜病变患者视野缺损的疗效研究[J].检验医学与临床,2016,13(17):2474-2475,2478,3.

检验医学与临床

1672-9455

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