临床输血与检验2016，Vol.18Issue(5)：446-447,448,3.DOI:10.3969/j.issn.1671-2587.2016.05.013
重型和中间型β-地中海贫血患儿输注洗涤红细胞的效果比较
A Comparative Investigation of the Therapuetic Effect in Children with β-thalassemia and Received Transfusion ;of Washed Erythrocytes
孙俊波 1陆应玉1
作者信息
- 1. 230601 合肥，安徽医科大学第二附属医院输血科
- 折叠
摘要
Abstract
Objective To analyze the effect of washed red blood cells(wRBC) transfusion in treatment of children with severe or intermediate β-thalassemia. Methods Twenty-three children at the age of 3~4 were selected and all of them had the same blood transfusion experience. Hemoglobin levels were tested in the children who sufferred from severe or moderateβ-thalassemia and underwent 21 times of blood transfusion with wRBC in each type of disease. and frequency of adverse effects of transfusion was observed. Results All the children investgated showed no adverse transfusion reaction. Children with severe type of β-thalassemia exhibited a lower increase of hemoglobin [(1.62±0.26) g/L per kg] than those with moderate type of the disease[(1.17±0.23) g/L per kg] after use of one unit of wRBC(P<0.05). Conclusion Hemoglobin level improvement in the children with severe type of β-thalassemia is not remarkable when compared with those who have moderate type of the disease after wRBC transfusion. Clinically, a relative high level of hemoglobin, and transfusion safety as well, should be ensured during wRBC transfusion.关键词
β-地中海贫血/输血/洗涤红细胞Key words
β-thalassemia/Blood transfusion/Washed red blood cell分类
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孙俊波,陆应玉..重型和中间型β-地中海贫血患儿输注洗涤红细胞的效果比较[J].临床输血与检验,2016,18(5):446-447,448,3.
