药学研究2016，Vol.35Issue(9)：538-541,4.DOI:10.13506/j.cnki.jpr.2016.09.013
线栓法致大鼠MCAO/IR模型缺血/再灌注时间与发病机制研究进展
Research progress on the mechanism and IR time in MCAO/IR model rats with string-fastenting method
陈丹丹 1谢晓芳 2敖慧 1彭成3
作者信息
- 1. 成都中医药大学，四川 成都610075
- 2. 雅安职业技术学院，四川 雅安 625000
- 3. 中药资源系统研究与开发利用省部共建国家重点实验室培育基地，四川 成都 610075
- 折叠
摘要
Abstract
The MCAO/IR model in rats induced by thread embolism in middle cerebral artery is the most common used animal model in the research of ischemic brain injury.In recent years,many researches has been conducted on this animal model.This article reviewed the correlation in the time of ischemia-reperfusion( IR)and the mechanism,aimed to provide references for the selection in IR time and evaluation index in drug research and also provide some clues for the future study in MCAO/IR model rats.关键词
线栓法/大脑中动脉线栓/缺血/再灌注时间/机制Key words
String-fastenting method/MCAO/Time of IR/Mechanism分类
医药卫生引用本文复制引用
陈丹丹,谢晓芳,敖慧,彭成..线栓法致大鼠MCAO/IR模型缺血/再灌注时间与发病机制研究进展[J].药学研究,2016,35(9):538-541,4.
