山东医药2016，Vol.56Issue(33)：18-21,4.DOI:10.3969/j.issn.1002-266X.2016.33.006
Amplatzer血管塞经导管封堵儿童冠状动脉瘘的临床疗效（附7例报告）
Transcatheter closure of coronary artery fistulae by using Amplatzer vascular plug in children:a clinical observation and follow-up study in 7 cases
摘要
Abstract
Objective To investigate the early and medium-term effect of transcatheter closure (TCC)of congenital coronary artery fistulae (CAF)by using Amplatzer vascular plug (AVP)in children and the occurrence of postoperative complications.Methods Preoperative,imaging,and postoperative follow-up data were collected from 7 patients treated with transcatheter closure of CAFs using AVPⅠ or AVPⅡ,and then we analyzed the relationships between the clinical effi-cacy,postoperative complications and closure way,anticoagulation.Results Seven cases all underwent successful TCC with 1 case of AVPI and 6 cases of AVP Ⅱ.A no-residual-shunt rate was 71.4% (5 /7)right after deploying devices.The period of postoperative follow-up was 4-36 months.Postoperative C /T ratio and diameter of right ventricle were less than the baseline levels (all P <0.05).All EF% was in normal range postoperatively.Of 7 cases,3 took aspirin for 6 months after TCC,2 for 3 months,1 for 3 days,and 1 did not take any.In 1 case a move of the device was noticed with a prominent re-sidual shunt,which reduced gradually after discontinuance of aspirin therapy.In another case a prominent residual shunt was found but no improvement after discontinuance of medication,resulting in another TCC by coils.In all cases no throm-botic or embolic event was found.Conclusions TCC by AVPⅠ /AVPⅡ in children can reduced shunting and relieve symptoms.Residual shunt and migration of device may be its common complications.We should consider the residual shunt in postoperative anticoagulating or antiplatelet therapy.关键词
冠状动脉瘘/介入封堵术/儿童/Amplatzer血管塞Key words
coronary artery fistula/interventional occluding therapy/child/Amplatzer vascular plug分类
医药卫生引用本文复制引用
李轩狄,林约瑟,李淑娟,朱玲,张兴,覃有振,李运泉,王慧深..Amplatzer血管塞经导管封堵儿童冠状动脉瘘的临床疗效（附7例报告）[J].山东医药,2016,56(33):18-21,4.基金项目
教育部博士点基金资助课题（20130171110048）。 （）
