摘要
Abstract
Objective to compare the efficacy study of rifapentine and rifampicin for the treatment of pulmonary tuberculosis. Methods research objects between 2010.1~2011.1 treated in our hospital from 800 pulmonary tuberculosis patients by digital table method were divided into observation group and control group, each of 400 cases randomly. Two groups of patients were given isoniazid, pyrazinamide, ethambutol hydrochloride oral treatment, given rifampicin capsule treatment group on the basis of the control, the observation group give rifapentine capsules for treatment and time of the two groups of patients are 6 months, compared two groups of efficacy, adverse reactions and treatment before and after glutamate amino shift enzyme (ALT), aspartate amino transfer enzyme (AST) levels. Results 6 months after treatment, the total effective rate of the observation group was 87.75%, significantly higher than the control group (P<0.05). The incidence of gastrointestinal reaction and leukocyte reduction in the observation group were significantly lower than those in the control group (P<0.05). The AST and ALT levels in the two groups were significantly higher than those in the control group (P<0.05). Conclusion rifapentine for efficacy in the treatment of pulmonary tuberculosis is exact, adverse reactions occurred rate is low, small liver damage of patients, it is worth popularizing and applying in clinical.关键词
肺结核/利福喷丁/利福平/疗效对比Key words
pulmonary tuberculosis/rifapentine/rifampicin/curative effect分类
医药卫生
