血管紧张素II及其受体与恶性肿瘤关系的研究进展OA北大核心CSCDCSTPCD
Advance in Research of Angiotensin II and Its Receptor and Malignant Tumor
血管紧张素II（angiotensin II, AngII）是由8个氨基酸组成的线性小肽，是肾素-血管紧张素系统（re-nin-angiotensinsystem, ARS）主要的效应因子。AngII主要的作用受体有两个，血管紧张素II1型（angiotensin II 1 recep-tor, AT1R）和AT2R分别是AngII作用于靶细胞表面的特异性G蛋白偶联1型和2型受体。AngII通过上述两种受体参与调节血管舒缩、水盐平衡、炎性反应、细…查看全部>>
Angiotensin AngII, a linear small peptide,which is composed of eight amino acids, is the main effectors of renin-angiotensin systen (Renin-angiotensin system, ARS). AngII, a main biopolypeptide of the ARS, has important patho-physiologic in effects participating in cardiac hypertrophy, vascular cell proproliferation, inlfammation and tissue remodeling through G-protein-coupled receptors. In recent years, Ang II can promote tumor cell proliferation, tumor ves…查看全部>>
孙鹿璐;史健
050000石家庄，河北医科大学050000石家庄，河北省肿瘤医院肿瘤内科
肿瘤血管紧张素II血管紧张素II1型受体血管紧张素II2型受体
TumorAngiotensin IIAngiotensin II 1 receptorAngiotensin II 2 receptor
《中国肺癌杂志》 2016 (9)
615-619,5
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