中国康复2016，Vol.31Issue(4)：243-245,3.DOI:10.3870/zgkf.2016.04.001
氦氖激光对退变颞下颌关节 BMP-2表达的影响
Effects of He-Ne laser on BMP-2 expression in degenerated temporomandibular joint of rabbits
摘要
Abstract
Objective:To observe the effects of He-Ne laser on the expression of BMP-2 in degenerated tem-poromandibular joint of rabbits,explore its protective role and mechanism in relieving temporomandibular joint de-generation and provide the basis for clinical application of He-Ne laser in the treatment of temporomandibular joint osteoarthritis.Methods:Forty New Zealand white rabbits were randomly divided into 4 groups:normal group, sham model group,model group and treatment group,10 in each group.The specimens were harvested at 1st,and 11th day after modeling.The animal model of temporomandibular joint disease was established by the methods of ChangJia.He-Ne laser was rayed at Jiache,Shangguan,Xiaguan,Tinggong,Yifeng points for 10 days in the treat-ment group.In the sham model group,the joint capsule was incised and sutured.The animals were killed at 1st, and 11th day and the protein expression of BMP-2 in temporomandibular joints was examined by Western blotting. Results:BMP-2 protein expression had no statistically significant difference between different time points in the nor-mal group and the sham model group,but that was up-regulated in the treatment group after He-Ne laser treatment for 10 days.Conclusions:He-Ne laser on acupoints may protect the degenerated temporomandibular joint through up-regulating the expression of BMP-2.关键词
氦氖激光/颞下颌关节退变/BMP-2Key words
He-Ne Laser/temporomandibular joint degeneration/BMP-2分类
医药卫生引用本文复制引用
毛凯平,邹璟,李解,姜梦雅,高桃珍..氦氖激光对退变颞下颌关节 BMP-2表达的影响[J].中国康复,2016,31(4):243-245,3.基金项目
武汉市卫生科研项目 （）
