中国社区医师2016，Vol.32Issue(27)：42-43,2.DOI:10.3969/j.issn.1007-614x.2016.27.24
恩替卡韦治疗乙肝病毒耐药导致慢性重型肝炎的临床效果观察
Clinical effect observation of entecavir in the treatment of hepatitis B virus resistance leading to chronic severe hepatitis
摘要
Abstract
Objective:To explore the effect of entecavir in the treatment of hepatitis B virus resistance leading to chronic severe hepatitis.Methods: 62 patients with chronic severe hepatitis caused by hepatitis B virus resistance.They were divided into the control group and the observation group with 31 cases in each according to the random number table method.The control group was given the basic treatment.The observation group added with the entecavir treatment.Results:After the treatment,the mortality rate of the observation group was significantly lower than that of the control group(P<0.05);the HBV-DNA negative conversion rate was higher than that of the control group(P<0.05);the liver function improvement of the observation group patients was better than that of the control group,and the level of Alb was significantly higher than that of the control group,and the level of ALT,AST and TBIL were significantly lower than those of the control group(P<0.05).Conclusion:Entecavir in the treatment of chronic severe hepatitis caused by hepatitis B virus resistance has obvious curative effect.It is beneficial to decrease the mortality rate of the patients and increase the HBV-DNA negative conversion rate,and improve the liver function.关键词
慢性重型肝炎/乙肝病毒耐药/恩替卡韦Key words
Chronic severe hepatitis/Hepatitis B virus resistance/Entecavir引用本文复制引用
金丽霞,王琳..恩替卡韦治疗乙肝病毒耐药导致慢性重型肝炎的临床效果观察[J].中国社区医师,2016,32(27):42-43,2.
