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马来酸桂派齐特与氯沙坦钾联合治疗早期糖尿病肾病的临床观察

马江华 张晓莉 谭晓丽 董明月

中国社区医师2016,Vol.32Issue(27):71-72,76,3.
中国社区医师2016,Vol.32Issue(27):71-72,76,3.DOI:10.3969/j.issn.1007-614x.2016.27.43

马来酸桂派齐特与氯沙坦钾联合治疗早期糖尿病肾病的临床观察

Clinical observation of cinepazide maleate combined with losartan potassium in the treatment of early diabetic nephropathy

马江华 1张晓莉 1谭晓丽 1董明月1

作者信息

  • 1. 100086火箭军总医院清河门诊
  • 折叠

摘要

Abstract

Objective:To explore the clinical efficacy and safety of cinepazide maleate combined with losartan potassium in the treatment of early diabetic nephropathy.Methods:68 patients with early diabetic nephropathy were randomly divided into the control group and the treatment group.The control group was treated with losartan potassium tablets.The treatment group was treated with cinepazide maleate injection on the basis of the control group.We compared the therapeutic effect of two groups. Results:①After treatment,UAER,renal function and blood pressure of the two groups were decreased(P<0.05),and the treatment group was significantly lower than that in the control group(P<0.05).②After treatment,in the treatment group,TC,TG and LDL-C were significantly decreased,HDL-C was elevated(P<0.05),while the control group had no significant change(P>0.05).③The total effective rate of the treatment group was significantly higher than that of the control group(P<0.05). ④ There was no significant difference in the incidence of adverse reactions between groups(P>0.05).Conclusion:The clinical efficacy of cinepazide maleate combined with losartan potassium in the treatment of early diabetic nephropathy was significant,and the security was high.

关键词

氯沙坦钾/马来酸桂派齐特注射液/早期糖尿病肾病

Key words

Losartan potassium/Cinepazide maleate injection/Early diabetic nephropathy

引用本文复制引用

马江华,张晓莉,谭晓丽,董明月..马来酸桂派齐特与氯沙坦钾联合治疗早期糖尿病肾病的临床观察[J].中国社区医师,2016,32(27):71-72,76,3.

中国社区医师

1007-614X

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