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姜黄素对A549裸鼠移植瘤影响的网状Meta分析

杨佳卉 张雅婷 唐佳 沈克非 王万聪 陈卿斌 黄鹏 田金徽

中国药物评价2016,Vol.33Issue(4):197-200,4.
中国药物评价2016,Vol.33Issue(4):197-200,4.

姜黄素对A549裸鼠移植瘤影响的网状Meta分析

Network Meta-analysis of the Effects of Curcumin on Human Lung Adenocarcinoma A549 Xenografted Tumor in Nude Mice

杨佳卉 1张雅婷 2唐佳 1沈克非 2王万聪 1陈卿斌 1黄鹏 2田金徽1

作者信息

  • 1. 兰州大学循证医学中心,兰州大学基础医学院,甘肃兰州730000
  • 2. 兰州大学第一临床医学院,甘肃兰州730000
  • 折叠

摘要

Abstract

Objective:To assess the effect of curcumin on human lung adenocarcinoma A549 xenografted tumor in nude mice.Meth-ods:We searched major Chinese database.The animal studies of curcumin on human lung adenocarcinoma A549 xenografted tumor in nude mice were including,the quality of including studies were assessed by SYRCLE′s risk of bias tool, and the related data were ana-lyzed by STATA13.0 software.Results:7 studies were included, the network Meta-analysis showed that, compared with the no treat-ment, curcumin could reduce the mean volume and weight of the xenografted tumor, and decrease microvessel density,at the same time, curcumin combined with cisplatin could increase the effect.Conclusion:The current evidence showed that curcumin could significantly effects on human lung adenocarcinoma A549 xenografted tumor in nude mice.

关键词

姜黄素/A549/网状Meta分析

Key words

Curcumin/A549/Network Meta-analysis

分类

医药卫生

引用本文复制引用

杨佳卉,张雅婷,唐佳,沈克非,王万聪,陈卿斌,黄鹏,田金徽..姜黄素对A549裸鼠移植瘤影响的网状Meta分析[J].中国药物评价,2016,33(4):197-200,4.

基金项目

甘肃省循证医学与临床转化重点实验室开放基金;兰州大学中央高校基本科研业务专项资金资助 ()

中国药物评价

2095-3593

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