中国卒中杂志2016，Vol.11Issue(9)：743-746,4.DOI:10.3969/j.issn.1673-5765.2016.09.006
青年与中老年脑梗死的对比研究
A Comparative Study of Cerebral Infarction between Young Adults and the Elderly
李振华 1杨清成 1张建刚 1郭艳平 1吴海香 1王永姣 1黄莹莹 1李庆霞1
作者信息
- 1. 1455000 安阳安阳市人民医院神经内科2新乡医学院研究生处
- 折叠
摘要
Abstract
Objective To investigate the differences of risk factors and etiology among different age groups of youth and middle aged & elderly people. Methods A total of 148 cases of youth cerebral infarction inpatients were separated into two groups: 18 to 35 years old group and 36 to 45 years old group. And 232 cases of middle aged & elderly inpatients (older than 45 years) in the same period were collected as control group, the distribution of risk factors and stroke subtypes were compared statistically among groups. Results (1) In 18 to 35 years old group, the top three risk factors were hyperhomocysteinemia (HHcy) (66.7%), hyperlipemia (40.7%) and hypertension (33.3%). In 36 to 45 years old group, the three most frequent risk factors were hypertension (59.5%), HHcy (56.2%) and hyperlipemia (47.1%). In the elderly group, the three most common risk factors were hypertension (72.4%), HHcy (54.7%) and hyperlipemia (48.7%). (2) The frequencies of hypertension and diabetes in elderly group were observed to be higher than that in 18 to 35 years old group (P<0.001,P=0.014) and 36 to 45 years old group (P<0.001,P<0.001), which was lower in 18 to 35 years old group than in 36 to 45 years old group (P=0.009,P<0.001). The exposure of heavy smoking was signiifcantly lower in 18 to 35 years old group than that in 36 to 45 years old group (P=0.006) and elderly group (P<0.001). (3) The proportion of undetermined etiology was highest in 18 to 35 years old group, significantly higher than in elderly group (37.0%vs 27.6%,P=0.013). The proportion of large artery atherosclerosis was highest in 36 to 45 years old group and elderly group (50.4% and 58.2%), were signiifcantly higher than that (25.9%) in 18 to 35 years old group (P=0.021,P=0.014). Conclusion Similar to the elderly group, the top three risk factors are hypertension, HHcy and hyperlipemia in 36 to 45 years old group, and large artery atherosclerosis is the leading cause of stroke. The difference is that HHcy, hyperlipemia and hypertension are the former three risk factors in 18 to 35 years old group, and most of patients are of unknown etiology.关键词
危险因素/病因/脑梗死Key words
Risk factors/Etiology/Cerebral infarction引用本文复制引用
李振华,杨清成,张建刚,郭艳平,吴海香,王永姣,黄莹莹,李庆霞..青年与中老年脑梗死的对比研究[J].中国卒中杂志,2016,11(9):743-746,4.
