摘要
Abstract
Objective To investigate the differences of risk factors and one year prognosis in patients with anterior and posterior circulation infarct. Methods The acute ischemic stroke patients in the Chinese National Stroke Registry (CNSR) were categorized according to Oxfordshire Community Stroke Project (OCSP). Anterior circulation infarct (ACI) was deifned as both total and partial anterior circulation. The patients with posterior circulation infarct (PCI) were compared with the ACI group in baseline information, and also recurrent stroke, death and poor outcome (modiifed Rankin Scale, mRS≥3) in 1- year follow-up after onset. Results Totally, 8099 patients with acute ischemic stroke were recruited in this study, including 6415 anterior circulation infarct (ACI) subject and 1684 posterior circulation infarct (PCI) subject. Compared with PCI group, the ACI subject were elder, had higher risk of atrial ifbrillation, and higher National Institutes of Health Stroke Scale (NIHSS) score on admission (P<0.001, respectively). PCI group had more male patients, higher risk of hypertension and diabetes mellitus (P<0.001, respectively). Multi-variables analysis showed, compared with PCI group, the ACI group had lower death risk on discharge (odds ratio [OR] 0.534, 95%conifdence interval [CI] 0.396-0.718,P<0.001), in 3-month (OR 0.592, 95%CI 0.472-0.744,P<0.001), 6-month (OR 0.636, 95%CI 0.516-0.785,P<0.001) and one-year follow-up (OR 0.719, 95%CI 0.591-0.876,P=0.001). The incidence of severe disability at discharge in ACI were significantly higher than PCI (OR 1.272 95%CI 1.075-1.505, P=0.005), while no signiifcant differences were found between the two groups in 3-, 6-, and 12-month follow-up. The recurrent stroke rates in PCI were similar to those of ACI in 3-, 6-, and 12-month follow-up. Conclusion Comparing to anterior circulation stroke, posterior circulation stroke has a higher rate of all cause death during 1-year follow up. The rate of severe disability and recurrent stroke are similar between the anterior and posterior circulation stroke.关键词
脑梗死/前循环/后循环/预后Key words
Cerebral infarction/Anterior circulation/Posterior circulation/Prognosis
