摘要
Abstract
Objective:To investigate the efficacy of TP induction chemotherapy combined with concurrent radiochemotherapy for locally advanced nasopharyngeal carcinoma.Method:130 cases of admitted patients with locally advanced nasopharyngeal carcinoma from August 2011 to September 2014 were selected as the research objects.They were randomly grouped as experimental group and control group,each consists of 65 cases.The patients in the experimental group were treated with TP induction chemotherapy combined with concurrent radiochemotherapy,whereas,patients in the control group were treated with PF induction chemotherapy combined with concurrent radiochemotherapy.Then,the curative effect was compared between the two groups.Result:The effective rate of the experimental group was 67.69%,and the effective rate of the control group was 69.23%,the difference between the two groups was not statistically significant(P>0.05).The average median progression-free survival time of patients in the experimental group was (12.4±3.1)months,and it was (9.3±1.6)months in the control group,the average median progression-free survival time of the experimental group was longer than that of the control group,the difference was statistically significant(P<0.05).Conclusion:The progression-free survival time of the patients can be prolonged by using the TP induction chemotherapy combined with concurrent radiochemotherapy,it is worthy of clinical application.关键词
TP方案/PF方案/局部晚期鼻咽癌/放化疗/生存时间Key words
TP scheme/PF scheme/Locally advanced nasopharyngeal carcinoma/Radiotherapy and chemotherapy/Survival time分类
医药卫生