中外医学研究2016，Vol.14Issue(26)：1-3,4,4.DOI:10.14033/j.cnki.cfmr.2016.26.001
血小板与冷沉淀联合输注在大出血临床治疗中应用的Meta分析
Therapeutic Effects of Co-infusion of Platelets and Cryoprecipitation in the Treatment of Patients with Massive Blood Loss:A Meta-analysis
摘要
Abstract
Objective:To systematically evaluate therapeutic effects of co-infusion of platelets and cryoprecipitation in the treatment of patients with massive blood loss.Method:The domestic lectures were retrieved from databases including CBM,CNKI,Wanfang Database.The meta-analyses were performed with RevMan 5.3 software for 15 randomized controlled trials(RCTs) of 1316 patients.Result:Compared with platelet group,PT,APTT and the average hemostasis time of co-infusion were all significantly shorten(P<0.01),the consumption of suspended red blood cells in 24 h was decreased significantly(P<0.01),and hemostatic efficiency was improved significantly(P<0.01),and post transfusion PLT had no significant changes(P>0.05).Compared with cryoprecipitation group, PT,APTT and the average hemostasis time of co-infusion were all significantly shorten(P<0.01),the consumption of suspended red blood cells in 24 h was decreased significantly(P<0.01),and hemostatic efficiency and post transfusion PLT were improved significantly(P<0.01).Conclusion:Co-infusion overcome the coagulation disorders in patients with massive blood loss,and it is the best method of hemostatic effect.It will win enough time for saving the patient’s precious life.关键词
血小板/冷沉淀/联合输注/大出血/Meta分析Key words
Platelets/Cryoprecipitation/Co-infusion/Massive blood loss/Meta-analysis分类
医药卫生引用本文复制引用
林姝婷,赖冬,龙敏..血小板与冷沉淀联合输注在大出血临床治疗中应用的Meta分析[J].中外医学研究,2016,14(26):1-3,4,4.基金项目
2014年厦门市科技计划项目(项目编号3502Z20149021) （项目编号3502Z20149021）
