摘要
Abstract
Objective: To study the effect of general anesthesia combined with epidural anesthesia on hemodynamics and stress level in elderly patients with hypertension.Methods: 80 cases of patients with admissions for laparoscopic gallbladder resection surgery in senile essential hypertension from 2014 March to March 2015 our hospital were researched. They were randomly divided into observation group and control group. Observation group were treated by implementation of general anesthesia combined with epidural anesthesia; control group received the implementation of a simple general anesthesia. Observed the changes of hemodynamic and stress level at different time points, the anesthesia recovery time and adverse reaction of the two groups.Results: Compared with the control group, SBP, DBP and HR in observation group decreased significantly; compared with the T1 (before operation) period, each index in T2 (intubation time), T3 (operation), T4 (atfer extubation) period in control group has obvious rise, the difference was statistically signiifcant (P<0.05); each index in T2, T3, T4 period in observation group slightly increased, with no statistical signiifcance (P>0.05); in the observation group, the levels of cortisol, epinephrine and endothelin in T2, T3 and T4 were lower than those in the control group, the difference was statistically signiifcant (P<0.05); the spontaneous breathing recovery time, extubation time and fully awake time in the observation group [(4.70±1.02, 7.80±2.26, 16.29±5.28) min] were less than those [(9.78±3.01, 15.83±3.29, 28.30±5.22) min] in the control group, the difference was statistically signiifcant (P<0.05); incidence rate of adverse reactions in the observation group [7.50% (3/40)] was less than that [42.50% (17/40)] in the control group, the difference was statistically significant (P<0.05).Conclusion: General anesthesia combined with epidural anesthesia can reduce the effect of laparoscopic cholecystectomy (LC) on hemodynamics and stress level in elderly patients with hypertension, and improve the prognosis and improve the therapeutic effect.关键词
全身麻醉/硬膜外麻醉/高血压老年患者/腹腔镜胆囊切除术患者/血流动力学/应激水平Key words
general anesthesia/epidural anesthesia/elderly patients with hypertension/laparoscopic cholecystectomy (LC) patients/hemodynamics/stress level
