摘要
Abstract
Objective: To study the effects of propofol compound fentanyl target controlled infusion on bispectral index (BIS) in hypertension patients.Methods: Selected 105 hypertension patients with propofol compound fentanyl target controlled infusion anesthesia from January 2015 to March 2016 in our hospital, divided the patients into three groups according to the fentanyl concentration of target controlled infusion, concentration of 2.0 ng/mL for group I, 3.0 ng/mL for group II, and 4.0 ng/mL for group III, and target concentrations of propofol in three groups were all 4 μg/mL, each group of 35 patients. Compared the mean arterial pressure, heart rate at each time point and the change of the electrical double frequency index in the home 5 min (T0), before intubation (T1), 1 min atfer intubation (T2), 3 min atfer intubation (T3) and 5 min atfer intubation (T4) among three groups of patients, and compared their waking time.Results: hTe mean arterial pressure and heart rate of T2, T3 time point in group I were signiifcantly higher than that of T1 time points; in group II, mean arterial pressure and heart rate of T2 time were signiifcantly higher than that of T1 time points, the differences were statistically signiifcant (P<0.05); at T2, T3, and T4 point, the brain electrical double-frequency index in group III was obviously lower than that of group I and II, the difference was statistically signiifcant (P<0.05); waking time in group III was obviously longer than that of group I, II, the difference was statistically signiifcant (P<0.05).Conclusion: Using propofol compound fentanyl target controlled infusion to anesthetize hypertension patients, the bispectral index will decrease with the concentration of fentanyl, reduce intubation stress reaction, and maintain stable hemodynamics.关键词
丙泊酚/瑞芬太尼/靶控输注/脑电双频指数Key words
propofol/fentanyl/target controlled infusion/bispectral index
