摘要
Abstract
Objective: To analyze the relationship between clinical features and clinical parameters of insulin resistance (IR)in the women with polycystic ovary syndrome (PCOS).Methods: Selected 72 cases of PCOS patients who were treated in our hospital from January 2013 to March 2015 as the study group, and divided into IR subgroup and non-IR subgroup according to whether or not the patients were associated with IR. And 55 cases of health women in child-bearing age were chosen as the control group. hTe general clinical data, hormone and biochemical indexes, blood glucose and insulin were collected and compared between the 2 groups. Insulin resistance and beta cell function parameters were calculated.Results: Compared with the control group, BMI, SBP and blood lipid index (TC, TG), and serum uric acid (SUA) in the study group increased signiifcantly, while age and DBP had no signiifcant difference (P>0.05); the incidence of IR in the study group is higher than that of control group (P<0.05); compared the hormone levels with the control group the study group, serum follicle-stimulating hormone (FSH), luteotropic hormone (LH), T, E2 in non-IR subgroups of the study group increased, and LH/FSH ratio increased; while compared between the two subgroups, the indicators were not statistically significant (P>0.05); compared the IR parameters between the two subgroups in the study group, HOMA-IR and FPG/FINS in IR subgroup increased significantly than those in the non-IR subgroup, the difference was statistically significant (P<0.05), while HOMA-IAI, ISI comp, and FPG/FINS decreased signiifcantly those in non-IR subgroup (P<0.05); as for the SG/SI ratio, there was no signiifcant difference between two groups (P>0.05); comparison of islet beta cell function parameters in two subgroups, HOMA-IS in IR subgroup was lower than that in non-IR subgroup, there was signiifcant difference (P<0.05). ΔI30/ΔG30 and DI value of the two groups showed no signiifcant difference (P>0.05).Conclusion: Insulin resistance rate in PCOS patients is higher than those in the normal population, insulin resistance improves the possibility of polycystic ovarian syndrome through a variety of ways, and increases the risk of glucose and lipid metabolism and endocrine disorders in patients. For patients with PCOS patients with or without insulin resistance has no difference with the disturbance of sex hormone level.关键词
多囊卵巢综合征/胰岛素抵抗/分析Key words
polycystic ovarian syndrome (PCOS)/insulin resistance (IR)/analysis
