中华骨质疏松和骨矿盐疾病杂志2016,Vol.9Issue(3):323-329,7.DOI:10.3969/j.issn.1674-2591.2016.03.017
姜黄素对骨骼系统的影响
Effect of curcumin on bone
摘要
Abstract
Curcumin is a natural polyphenolic compound which is isolated from the rhizome of Curcuma longa. It predominately resides in its keto form in acidic and neutral conditions and solid phase .The chemical structure makes it much less soluble in water .Curcumin has a variety of pharmacologically activities .Curcumin inhibits the proliferation and bone-resorption function of osteoclasts , as well as the proliferation of osteoblasts in vitro .However, the specific direction of its effect on bone remodeling in vivo remains controversial .With the further research , the effect of curcumin could be much clearer and the following application prospects would be much broader .关键词
姜黄素/骨质疏松/成骨细胞/破骨细胞Key words
curcumin/osteoporosis/osteoblasts/osteoclasts分类
医药卫生引用本文复制引用
陈之光,薛今琦,付勤..姜黄素对骨骼系统的影响[J].中华骨质疏松和骨矿盐疾病杂志,2016,9(3):323-329,7.基金项目
国家自然科学基金(81370981);盛京自由研究者基金 ()