川北医学院学报2016，Vol.31Issue(5)：741-744,4.DOI:10.3969/j.issn.1005-3697.2016.05.034
能谱CT测量活体甲状腺碘含量及其准确性的研究
Study on the gemstone spectral imaging of thyroid iodine content measure-ment in vivo and its accuracy
何磊 1柳溪 1陈英敏 1刘蓉辉 1贾秀川 1康林2
作者信息
- 1. 河北省人民医院医学影像科
- 2. 河北省人民医院病理科，河北 石家庄 050051
- 折叠
摘要
Abstract
Objective:To measure the iodine concentration of the living the normal value base on material imaging measure-ment,and to study its accuracy.Methods:Total of 76 cases of suspected cervical or thyroid disease underwent gemstone spectral ima-ging.Then the imagine data were transmitted to AW 4.4 station to obtain monochromatic images of optimal contrast to-noise ratio (CNR)and iodion-based images with GSI Viewer.Iodine,water concentration of ROl in thyroid tissue was measured.In addition,35 cases of surgical specimens of nodular goiter were collected,and select normal thyroid tissue of adjacent nodules.The iodine content of samples was measured by As-Ce-Catalytic spectrophotometry.Relationship between iodine and water concentration with it were ana-lyzed.Results:The difference of iodine concentration between male and female patients was statistically significant (P <0.05 ).There was no statistical difference between 40 -60 group and >60 group(P >0.05),while differences between other groups were statistically significant (P <0.05 and P <0.01 ).The comparison among groups of water concentration were not statistically significant(P >0.05). In nodular goiter group,the iodine concentration of isolated specimen is 0.173-0.64 mg /g,mean(0.357 ±0.064)mg /g.Statistical a-nalysis showed correlation (r =0.820,P <0.01 )between iodine concentration (0.28 -2.31 mg /mL,mean(1 .38 ±0.56)mg /mL) and the iodine concentration of isolated specimen.There was no correlation (r =0.064,P >0.05 ) between water concentration (1 040.73 -1 067.17 mg /mL,mean(1 055.93 ±1 1 .16 )mg /mL)and the iodine concentration of isolated specimen.Conclusion:Gemstone spectral imaging can be more direct and more accurate quantifying of iodine concentration of normal thyroid.This can provide reference for the diagnosis of thyroid diseases.关键词
体层摄影术/X线计算机/甲状腺/碘密度/能谱成像Key words
Tomography/X-ray computed/Thyroid/Iodine concentration/Gemstone spectral imagine分类
医药卫生引用本文复制引用
何磊,柳溪,陈英敏,刘蓉辉,贾秀川,康林..能谱CT测量活体甲状腺碘含量及其准确性的研究[J].川北医学院学报,2016,31(5):741-744,4.
