动物医学进展2016，Vol.37Issue(10)：81-84,4.
rhEPO 对缺糖缺氧大鼠星形胶质细胞GLT-1和 GLAST 表达的影响
Effects of rhEPO on Expressions of GLT-1 and GLAST in Rat Astrocyte of Cultured by Oxygen-glucose Deprivation
摘要
Abstract
In order to study effects of rhEPO on the expressions of GLT-1 and GLAST in rat astrocytes cul-tured by oxygen-glucose deprivation,the astrocytes of rats cultured by oxygen-glucose deprivation were di-vided into three groups with different concentrations of rhEPO 0,20,100 U/mL and cultured for 6 hours by hypoxia-glucose deprivation.The real-time PCR and Western blot were used to detect the changes of mRNA and protein expressions of GLT-1 and GLAST,respectively.In comparison with OGD control,mR-NA and protein levels of GLT-1 were found to be increased in the groups of 20 and 100 U/mL rhEPO (P <0.05),but the changes of GLAST were not obvious(P >0.05).The changes of GLT-1 may be related to protective effects of rhEPO on astrocytes of rats cultured by oxygen-glucose deprivation.关键词
重组人促红细胞生成素/星形胶质细胞/GLT-1/GLAST/缺糖缺氧Key words
rhEPO/astrocyte/GLT-1/GLAST/oxygen-glucose deprivation分类
农业科技引用本文复制引用
庞一强,杨静,吴刚,汪静,姜树原..rhEPO 对缺糖缺氧大鼠星形胶质细胞GLT-1和 GLAST 表达的影响[J].动物医学进展,2016,37(10):81-84,4.基金项目
内蒙古自治区自然科学基金项目（2013MS1111）；包头市医药卫生科技计划项目 （）
