南方医科大学学报2016,Vol.36Issue(10):1305-1311,7.DOI:10.3969/j.issn.1673-4254.2016.10.01
脑卒中后抑郁症患者肠道菌群的多样性分析
Diversity of intestinal microflora in patients with depression after stroke
摘要
Abstract
Objective To investigate the changes in the population and distribution intestinal microflora and their relationship with depression in post-stroke patients. Method Fecal specimens were obtained from 32 patients with post-stroke depression and 30 healthy adults for gene sequencing of 16S RNA V3 region of the intestinal microorganism using Roche/45 high-throughput sequencing platform. Results The genus and species of intestinal bacteria showed significant differences between the post-stroke patients and health adults. Conclusion Significant changes in the structure of intestinal flora occur in patients with post-stroke depression.关键词
卒中后抑郁症/肠道菌群/多样性Key words
post-stroke depression/intestinal flora/diversity引用本文复制引用
范文涛,闫咏梅,别玉龙,王倩..脑卒中后抑郁症患者肠道菌群的多样性分析[J].南方医科大学学报,2016,36(10):1305-1311,7.基金项目
国家自然科学基金(81470188,81373840,81673832);陕西省教育厅项目(14JK1197);陕西省中医药管理局项目(13-LC073);陕西省科技厅社发公关项目(2016SF-375) Supported by National Natural Science Foundation of China (81470188,81373840,81673832) (81470188,81373840,81673832)