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脑卒中后抑郁症患者肠道菌群的多样性分析

范文涛 闫咏梅 别玉龙 王倩

南方医科大学学报2016,Vol.36Issue(10):1305-1311,7.
南方医科大学学报2016,Vol.36Issue(10):1305-1311,7.DOI:10.3969/j.issn.1673-4254.2016.10.01

脑卒中后抑郁症患者肠道菌群的多样性分析

Diversity of intestinal microflora in patients with depression after stroke

范文涛 1闫咏梅 1别玉龙 1王倩1

作者信息

  • 1. 陕西中医药大学,陕西 咸阳 712046
  • 折叠

摘要

Abstract

Objective To investigate the changes in the population and distribution intestinal microflora and their relationship with depression in post-stroke patients. Method Fecal specimens were obtained from 32 patients with post-stroke depression and 30 healthy adults for gene sequencing of 16S RNA V3 region of the intestinal microorganism using Roche/45 high-throughput sequencing platform. Results The genus and species of intestinal bacteria showed significant differences between the post-stroke patients and health adults. Conclusion Significant changes in the structure of intestinal flora occur in patients with post-stroke depression.

关键词

卒中后抑郁症/肠道菌群/多样性

Key words

post-stroke depression/intestinal flora/diversity

引用本文复制引用

范文涛,闫咏梅,别玉龙,王倩..脑卒中后抑郁症患者肠道菌群的多样性分析[J].南方医科大学学报,2016,36(10):1305-1311,7.

基金项目

国家自然科学基金(81470188,81373840,81673832);陕西省教育厅项目(14JK1197);陕西省中医药管理局项目(13-LC073);陕西省科技厅社发公关项目(2016SF-375) Supported by National Natural Science Foundation of China (81470188,81373840,81673832) (81470188,81373840,81673832)

南方医科大学学报

OA北大核心CSCDCSTPCDMEDLINE

1673-4254

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