南方医科大学学报2016，Vol.36Issue(10)：1312-1315,4.DOI:10.3969/j.issn.1673-4254.2016.10.02
早孕期胎儿大脑中动脉收缩期峰值流速、心胸比值与胎儿头臀长的相关性
Correlation analysis of fetal middle cerebral artery peak systolic velocity, cardiothoracic ra-tio and crown-rump length in early pregnancy
摘要
Abstract
Objective To explore the pattern of variations in middle cerebral artery peak systolic velocity (MCA PSV) and cardiothoracic ratio (CTR) during early pregnancy, establish their reference ranges and explore their correlation with the crown-rump length (CRL). Methods A total of 522 pregnant women with normal findings in antenatal examinations underwent routine color Doppler ultrasound examination to collect the data of MCA PSV, CTR and CRL. The reference ranges of MCA PSV and CTR for different CRL levels were established, and the correlation of MCA PSV and CTR with CRL was analyzed. Results During the first trimester, MCA PSV and CRL showed a moderate positive correlation with a correlation coefficient of 0.426 (P<0.001), while CTR and CRL showed no significant correlation (0.168, P<0.001). The reference range of MCA PSV was 14.35 (14.08-14.62) cm/s and that of CTR was 0.34 (0.33-0.34) during early pregnancy. Conclusion Color Doppler ultrasound is a safe and feasible modality to assess fetal MCA PSV and CTR for detecting fetal growth abnormalities in early pregnancy. The established reference ranges of MCA PSV and CTR offer a clinical theoretical basis for detectingα-thalassemia in early pregnancy.关键词
早孕/大脑中动脉收缩期峰值流速/心胸比值/头臀长Key words
early pregnancy/middle cerebral artery peak systolic velocity/cardiothoracic ratio/crown-rump length引用本文复制引用
邓许洁,陈翠华,裘毓雯,肖淑芳,廖淑欣,钟梅,杨芳..早孕期胎儿大脑中动脉收缩期峰值流速、心胸比值与胎儿头臀长的相关性[J].南方医科大学学报,2016,36(10):1312-1315,4.基金项目
国家自然科学基金（81401214） Supported by National Natural Science Foundation of China (81401214) （81401214）
