摘要
Abstract
Objective To explore the curative effect of gynecological surgery in the treatment of patients with malignant ovarian germ cell tumor (MOGCT) with reproductive requirement.Methods 77 patients with MOGCT with reproductive requirement were selected,and divided into adnexectomy group (37 cases),staging surgery group (31 cases),neoplasms resection group (9 cases) according to the operation methods.Observed operation time,intraoperative blood loss,pregnancy and delivery situation,complications,recurrence,deaths,and cumulative survival rate for five years of three groups.Results There were statistically significant differences in operation time,intraoperative blood loss,the incidence of postoperative complications among three groups (P<0.05),no statistically significant difference in the course of chemotherapy among three groups (P>0.05).After treatment,the rate of pregnancy and delivery in adnexectomy group were the highest (75.68%,72.97%),followed by 67.74%,64.52% in staging surgery group,66.67%,55.56% in neoplasms resection group,without statistically significant differences among three groups (P>0.05).There were statistically significant differences in the rate of recurrence,case fatality rate among three groups (P<0.05).Cumulative survival rate for five years of adnexectomy group,neoplasms resection group,staging surgery group were 100%,100%,90.32%,without statistically significant difference among three groups (P>0.05);cumulative disease free survival rate for five years of adnexectomy group,neoplasms resection group,staging surgery group were 100%,88.89%,83.87%,with statistically significant difference among three groups (P<0.05).Conclusion Adnexectomy combined with PVB chemotherapy regimen in the treatment of patients with MOGCT with reproductive requirement has ideal effect.关键词
卵巢恶性生殖细胞肿瘤/生育功能/妇科外科手术/疗效Key words
Malignant ovarian germ cell tumor/Reproductive function/Gynecological surgery/Effect