国际眼科杂志2016，Vol.16Issue(11)：2048-2052,5.DOI:10.3980/j.issn.1672-5123.2016.11.16
光动力疗法联合抗血管内皮生长因子药物治疗脉络膜新生血管的进展
Progress of photodynamic therapy combined with anti - VEGF for patients with choroidal neovascularization
摘要
Abstract
Choroidal neovascularization( CNV) is a common severe complication of ocular fundus diseases, with great potentiality to cause blindness. The treatments of CNV include photodynamic therapy ( PDT ) and anti-vascular endothelial growth factor( VEGF) therapy. However, PDT produces little visual benefits, and may result in ischemia, inflammatory responses, even the secondary expressions of VEGF. Anti-VEGF therapy sustained visual efficiency by repeated injections, causing economic burden and adverse effects related to injection. Recently, PDT combined with anti-VEGF therapy has progressed in laboratory and clinical research. Therefore, the combined modality therapy became one of the treatment options for CNV. In order to reduce the side effects of mono -therapy, further study is required to determine appropriate combinations and dosage.关键词
脉络膜新生血管/光动力疗法/抗血管内皮生长因子/联合治疗Key words
choroidal neovascularization/photodynamic therapy/anti-vascular endothelial growth factor/combined modality therapy引用本文复制引用
刘洋,黎蕾..光动力疗法联合抗血管内皮生长因子药物治疗脉络膜新生血管的进展[J].国际眼科杂志,2016,16(11):2048-2052,5.基金项目
上海市自然科学基金(No.12ZR1405000) （No.12ZR1405000）
