王环君 1皮银珍 1谭荣 1李琳 1刘罗坤 1胡丽1
作者信息
- 1. 长沙市第一医院内分泌代谢科，湖南 长沙410005
- 折叠
摘要
Abstract
Objective To investigate the correlation factors of carotid intia￣media thickness( IMT) in new onset type 2 diabetes mellitus( T2DM) with metabolic syndrome( MS) . Methods A total of 80 new onset type 2 diabetes in our de￣partment were recruited in the study from July 2015 to February 2016,and then further divided into T2DM group ( 40 ca￣ses)and T2DM complicated with MS group (40 cases).We measured the age,sex,blood pressure(BP),body mass index ( BMI) ,and the the insulin resistance was determined by homeostasis model assessment of insulin resistance( HOMA￣IR) , detected lipid level,high density lipoprotein￣cholesterol( HDL￣C) ,the hemoglobin A1c level( HbA1c) ,fasting plasma glu￣cose(FPG),2￣hour postprandial plasma glucose (2hPG) and fasting insulin concentration(FINS) and postprandial insulin (PINS).We evaluated all the patients’ IMT,and analysed the relationship between IMT and these factors. Results The patients’ age,BMI,TC,TG,LDL,HOMA￣IR and IMT were higher in new onset T2DM patients complicated with MS group than in T2DM group(P<0.05),HDL was lower(P<0.05).There was positive correlation between IMT with age,TG,LDL, HOMA￣IR and complicated with MS(P<0.05),and negative correlation with HDL(P<0.05).The IMT was related to age, LDL,insulin resistence and complicated with MS respectively. Conclusion The patients with new onset T2DM suffering from MS were more susceptible to diabetic macrovascular disease compared to the ones just with T2DM.The age,LDL,insu￣lin resistance and suffering from MS were risk factors for new onset type 2 diabetes with carotid atherosclerosis. We should try the best to control these factors,then to prevent the occurrence and development of diabetic macroangiopathy.关键词
新发2型糖尿病/代谢综合征/颈动脉内膜中层厚度Key words
new onset type 2 diabetes mellitus/metabolic syndrome/carotid intima￣media thickness分类
医药卫生
