中南医学科学杂志2016,Vol.44Issue(5):536-539,4.DOI:10.15972/j.cnki.43-1509/r.2016.05.013
某ICU医院感染多重耐药菌构成及药敏分析
Composition and Drug Susceptibility Analysis of Multi-drug Resistant Bacteria in the ICU Nosocomial Infection
闫晓笑 1杨立明 1苗慧慧1
作者信息
- 1. 山西医科大学附属太钢总医院重症医学科,山西 太原030003
- 折叠
摘要
Abstract
Objective To observe and analyze multiple drug ̄resistant bacteria( MORO) hospital infection and drug susceptibility in ICU,to provide basis for prevention and control of hospital infection in critical patients. Methods A ret ̄rospective survey of MDRO infection was made in hospital ICU from March 2010 to March 2014. Results 120 strains MDRO were detected and it accounted for 55.30% of nosocomial infection.The corporation of the Gram ̄positive(G+) bacte ̄ria were more(55.00%).The top 5 MDRO were Enterococcus faecalis (24.20%),Staphylococcus aureus (20.80%),Bau ̄man Acinetobacter (17.50%),Escherichia coli (8.30%) and Pseudomonas aeruginosa (6.70%).The supreme prevalence of MDRO was the stenotrophomonas maltophilia(SMA).It has higher susceptibility to trimesulf,ofloxacin and ciprofloxacin. Pseudomonas aeruginosa is the most sensitive MDRO to Amikacin (75.00%).Bauman Acinetobacter shows extensive bacte ̄rial antibiotic resistance.The sensitivity of imipenem,meropenem and Cefoperazone/Shubatan were 42.10%,35.70% and 21. 10%.One strain of Enterococcus faecali was resistant to vancomycin and one Staphylococcus aureus was too. Various Gram ̄positive MDRO is susceptible to minocycline ( 59. 30%~83. 30%) . Conclusion The detection rate of MDRO in ICU is high,the category of resistance to antimicrobial drugs is of large variety.The rational selection and use of antibiotics should be based on the results of monitoring of bacterial resistance and drug ̄sensitivity tests. Keeping the patients apart, strict medical facility sterilization and intensive hand hygiene are very important preventive measures for infections.关键词
ICU/院内感染/多重耐药菌/抗菌药物敏感试验Key words
Intensive care unit/Nosocomial infection/Mutidrug ̄resistant organism/Antibiotic susceptibility test分类
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闫晓笑,杨立明,苗慧慧..某ICU医院感染多重耐药菌构成及药敏分析[J].中南医学科学杂志,2016,44(5):536-539,4.