现代检验医学杂志2016,Vol.31Issue(5):88-90,3.DOI:10.3969/j.issn.1671-7414.2016.05.023
骨科医院多重耐药鲍曼不动杆菌耐药性与基因同源性分析
Drug Resistance and Homology Analysis of Multi-drug Resistant Acinetobacter Baumannii in Orthopaedic Hospital
摘要
Abstract
Objective To investigate the drug resistance and homology status of Multi-drug Resistant AcinetobacterBauman-nii (MDR-AB)in orthopaedic hospital.Methods 34 strains MDR-AB were isolated from 2016.1~2016.7 for DNA extrac-tion and were typed by repetitive extragenic palindromie-polyrnerase chain reaction (REP-PCR).Results The resistance rate of MDR-AB were ≥70% to 15 of 17 antimicrobials,except to cotrimoxazole (14%)and levofloxacin (61%),34 strains of MDR-AB were divided into three types by REP-PCR including typeⅠ,typeⅡ and typeⅢ.Conclusion Drug resistance of MDR-AB was severe and mainly composed of the same genotype (typeⅠ).Rational use of antimicrobial and regular mo-nitoring of drug resistance is necessary to reduce the nosocomial transmission.关键词
多重耐药鲍曼不动杆菌/耐药性/基因外回文重复序列聚合酶链式反应/同源性Key words
MDR-AB/drug resistance/REP-PCR/homology分类
医药卫生引用本文复制引用
赵和平,王冀邯,蒋文艳,张蓓,赵静,于燕..骨科医院多重耐药鲍曼不动杆菌耐药性与基因同源性分析[J].现代检验医学杂志,2016,31(5):88-90,3.基金项目
西安市卫生局科技计划项目(J2014033)。 ()