现代检验医学杂志2016，Vol.31Issue(5)：100-102,3.DOI:10.3969/j.issn.1671-7414.2016.05.027
N-端脑钠肽前体测定在高血压疾病中的应用研究
Application on NT-proBNP in Patients with Essential Hypertension
李小侠 1詹颉 1张华 1党小军 1赵海 1奚逢瑜 1李博1
作者信息
- 1. 陕西省人民医院检验科，西安 710068
- 折叠
摘要
Abstract
Objective To study the N terminal pro brain natriuretic peptide (NT-proBNP)in serum of hypertension patients. Methods 152 patients with hypertension were included in this study.According to the different degree and development of hypertension,152 patients were divided into three different grade group of hypertension:first grade of hypertension group (30 patients),second grade of hypertension group (36 patients)and third grade of hypertension group (86 patients).And the 86 patients were divided into hypertension group (40 patients)and hypertension with diabetes group (46 patients)re-spectively,comparaed with the level of NT-proBNP in serum of different hypertension grade groups.Results The levels of the NT-proBNP in serum were 68±44,122±31 and 834±309 pg/ml of first grade of hypertension group,second grade of hypertension group and third grade of hypertension group,respectively.The level of the NT-proBNP was gradually increased with grade of hypertension (t=2.455,3.561,P<0.01).The level of the NT-proBNP (1 178±864 pg/ml)of hypertension with diabetes group was significantly higher than hypertension group (599±411 pg/ml)(t=3.785,P<0.01).Conclusion The level of NT-proBNP can obj ectively reflect the grade of the disease in patients with hypertension.it is a certain signifi-cance guiding for monitoring the clinical treatment of the disease.关键词
脑钠肽/N-端脑钠肽前体/高血压/糖尿病Key words
BNP/NT-proBNP/Hypertension/diabetes分类
医药卫生引用本文复制引用
李小侠,詹颉,张华,党小军,赵海,奚逢瑜,李博..N-端脑钠肽前体测定在高血压疾病中的应用研究[J].现代检验医学杂志,2016,31(5):100-102,3.
