现代检验医学杂志2016，Vol.31Issue(5)：132-133,2.DOI:10.3969/j.issn.1671-7414.2016.05.038
粘着斑激酶在前列腺癌中表达的研究
Research on Expression of FAK in Prostate Carcinoma
廖洪利 1米叶赛尔·阿不都拉1
作者信息
- 1. 新疆喀什地区第一人民医院检验科，新疆喀什 844000
- 折叠
摘要
Abstract
Objective To investigate the relationships between expression of FAK and Prostate Carcinoma (PC)morbidity. Methods By surgery,get cancer tissue and para-carcinama tissue from 60 cases PC.To detect FAK expression by immuno-histochemical.To extract total RNA by Trizol.To detect the FAK mRNA by RT-PCR,and analysis these data.Results FAK expression level in cancer tissue was higher than that in para-carcinama tissue.There was statistical difference between them (χ2=72.55,P<0.01).mRNA expression levels of FAK in cancer tissue showed significant higher than the levels in para-carcinama tissue (t=30.51,P<0.01).According to lymphatic metastasis,the expression positive cases of FAK in pN0M0 classification were lower than these in pN3M1 classification,and mRNA expression levels of FAK were the same re-sults.There were clearly statistical distinctive (t=25.43,P<0.01).Conclusion The expression of FAK in PC cells was as-sociated with tumor invasion.关键词
前列腺癌/粘着斑激酶(FAK)/免疫组化Key words
prostate carcinoma(PC)/focal adhesion kinase (FAK)/immunohistochemical分类
医药卫生引用本文复制引用
廖洪利,米叶赛尔·阿不都拉..粘着斑激酶在前列腺癌中表达的研究[J].现代检验医学杂志,2016,31(5):132-133,2.
