现代检验医学杂志2016，Vol.31Issue(5)：142-143,146,3.DOI:10.3969/j.issn.1671-7414.2016.05.042
女性不孕症患者抗心磷脂抗体和抗β2-糖蛋白1抗体的检测及临床应用
Detection and Clinic Application of Antiphospholipid Antibody and Anti-β2-GPⅠ in Female Infertility
黄杰 1王青 1李良军 2张策2
作者信息
- 1. 大连市妇女儿童医疗中心检验科，辽宁大连 116027
- 2. 大连医科大学附属第二医院，辽宁大连 116023
- 折叠
摘要
Abstract
Objective To analyze the correlation of different antiphospholipid antibody isotypes in female infertility.Methods Selected 296 patients with female infertility and 31 normal female between May 2015 to August 2015 in Dalian Women’s and Children’s Medical Centre.All the antibodies were detected by chemilumininescence.The positiverate of antipholipid an-tibodies in female infertility patients and health controls were calculated.The concentrations of antiphospholipid antibodies in different groups were compared with Mann-Whitney U test.Results The positive rate of aCL IgG of female infertility and normal female were 0.34% and 0.00%.The positive rate of aCL IgM of female infertility and normal female were 1.35%and 0.00%.The positive rate ofβ2 GPⅠ IgG of female infertility and normal female were 0.00% and 0.00%.The positive rate ofβ2 GPⅠ IgM of female infertility and normal female were 0.34% and 0.00%.aCL IgG were differet beween female infertility and normal female (P=0.013),others had on significant difference.Conclusion Need to detect LA,combined with aCL and anti-β2 GPⅠ,exclusively diagnose APS,layed the foundation of sequential treatment.关键词
抗心磷脂抗体/抗β2 糖蛋白Ⅰ抗体/女性不孕症Key words
anti cardiolipin antibody/anti-betaβ2-Glycoprotein Ⅰ antibody/female infertility分类
医药卫生引用本文复制引用
黄杰,王青,李良军,张策..女性不孕症患者抗心磷脂抗体和抗β2-糖蛋白1抗体的检测及临床应用[J].现代检验医学杂志,2016,31(5):142-143,146,3.
