针刺研究2016，Vol.41Issue(5)：440-446,7.DOI:10.13702/j.1000-0607.2016.05.014
电针对肝肾阴虚型类风湿关节炎患者关节功能的影响
Effects of Electroacupuncture on Joint Function in Rheumatoid Arthritis Patients of Liver-and Kidney-Yin Deficiency Type
摘要
Abstract
Objective To compare the effects between electroacupuncture (EA)plus western medicine and simple western medicine in improving clinical symptoms and local joint function of rheumatoid arthritis (RA)patients with yin deficiency of Liver and Kidney.Methods A total of 68 RA patients of yin deficiency of Liver and Kidney were equally randomized into EA+medication group and medication group (n =34 in each group).Both groups were given once-a-week methotrexate (7.5 mg/time)and once-a-day leflunomide (1 0 mg/time),while EA+medication group was additionally treated by EA at bilateral Ganshu (BL 1 8),Shenshu (BL 23),Xuanzhong (GB 39),Zusanli (ST 36),Taichong (LR 3),Hegu (LI 4)3 times/week.The treatment lasted for 1 2 weeks.The visual analogue scale (VAS,for assessing rest pain),swollen joint count (SJC),tender joint count (TJC),patient’s global assessment (PGA),physician’s global assessment (PhGA),traditional Chinese medicine (TCM)symp-tom scoring,28 joints activity index (disease activity score,DAS 28),American College of Rheumatology 20 (ACR 20,i.e. 20% of clinical improving rate),and health assessment questionnaire (HAQ)were assessed and erythrocyte sedimentation rate (ESR),serum C-reactive protein (CRP)levels were examined for comparison.Results Statistical differences were observed in before-after-treatment comparisons in both groups in reducing rest pain,SJC,TJC,serum CRP content,PGA and PhGA,HAQ scoring and DAS 28 (P <0.05,P <0.0 1 ).The ESR in the medication group and TCM symptom scoring of the EA+medication group were also significantly decreased after the treatment (P <0.05).The effects of the EA+medication group were superior to those of the medication group in reducing rest pain,SJC,TJC,TCM symptom and HAQ score,and the total effetive rate (P <0.05,90.9% vs 66.67%).Adverse reactions as pharyngeal obstruction sensation,anorexia,abdominal distension,etc. can be reduced by EA therapy coordinated with western medicine.Conclusion EA is effective in relieving symptom and joint function in RA patients with yin deficiency of Liver and Kidney.关键词
类风湿关节炎/肝肾阴虚型/电针/随机对照试验/关节功能Key words
Rheumatoid arthritis/Yin deficiency of Liver and Kidney type/Electroacupuncture/Randomized con-trolled trial/Joint function分类
医药卫生引用本文复制引用
周殷,朱俊,李连波,何天峰,陈潇毅,郑詠耀,陈云飞..电针对肝肾阴虚型类风湿关节炎患者关节功能的影响[J].针刺研究,2016,41(5):440-446,7.基金项目
上海市中医药事业发展三年行动计划重大研究(No.ZYSNXD-CCZDYJ 052) （No.ZYSNXD-CCZDYJ 052）
国家自然科学基金青年科学基金项目(No.81503599) （No.81503599）
