中国肺癌杂志2016，Vol.19Issue(10)：653-658,6.DOI:10.3779/j.issn.1009-3419.2016.10.03
72例肺腺鳞癌临床病理特点和预后因素分析
Clinicopathologic Features and Prognostic Implications in 72 Cases with Lung Adenosquamous Carcinoma
吴熙 1李峻岭 2陈舒兰 3于雷 1杨渤彦1
作者信息
- 1. 100021北京，国家癌症中心/中国医学科学院北京协和医学院肿瘤医院综合科
- 2. 100021北京，国家癌症中心/中国医学科学院北京协和医学院肿瘤医院内科
- 3. 100021北京，国家癌症中心/中国医学科学院北京协和医学院肿瘤医院病案室
- 折叠
摘要
Abstract
Background and objectiveAdenosquamous carcinoma (ASC) is a rare subtype of lung cancer, it is mixed glandular and squamous cell carcinoma with a more aggressive behavior and poor prognosis than the other histologic subtypes. hTe aim of the study was to explore the clinicopathological characteristics and prognostic factors of ASC.Methods A total of 72 patients were enrolled. We investigated clinicalpathological features and prognostic factors retrospectively.Results hTe overall 72 ASC patients’ median age was 34.7 months, 5-year survival rate was 14.9%. hTe inlfuence of tumor size, M stage, and N stage, gene mutation and surgery on the prognosis of patients show statistical signiifcance.Conclusion ASC is charac-terized by both histologic aggressiveness and adverse prognosis. We suggest the comprehensive therapy based on surgery, and given small molecule tyrosine kinase inhibitors (TKIs) treatment may prolong patients’ overall survival.关键词
肺肿瘤/腺鳞癌/临床病理/预后Key words
Lung neoplasms/Adenosquamous carcinoma/Clinicopathology/Prognosis引用本文复制引用
吴熙,李峻岭,陈舒兰,于雷,杨渤彦..72例肺腺鳞癌临床病理特点和预后因素分析[J].中国肺癌杂志,2016,19(10):653-658,6.
