摘要
Abstract
Background and objectiveLung cancer is a malignancy with high morbidity and mortality rates world-wide. Surgery is the preferred treatment for non-small cell lung cancer. hTis study aims to investigate the effects of video-as-sisted thoracoscopic surgery (VATS) lobectomy, VATS segmentectomy, and open thoracotomy on pulmonary function in the early postoperative stage and compare the difference among three groups.MethodsPulmonary function data of patients were collected from September 2015 to February 2016 in Department of hToracic Surgical Oncology, Cancer Hospital Chinese Academy of Medical Sciences. hTe patients were categorized according to operation methods into three groups, namely, VATS segmentectomy, VATS lobectomy, and open thoracotomy groups. Pulmonary function was assessed 1 day before the surgery, 3 days atfer the surgery, and 3 months atfer the surgery. Statistical analysis was performed with SPSS 20.0 through single-factor analysis of variance.Results Pulmonary function 3 days atfer the surgery was compared among the three groups. hTere was a signiifcant difference in forced vital capacity (FVC), FVC%, forced expiratory volume in one second (FEV1), FEV1%, peak ex-piratory lfow (PEF), maximal voluntary ventilation (MVV), transfer factor for carbon monoxide of lung (TLCO) and TLCO%(P values were as follows: 0.033, 0.042, 0.029, 0.045, 0.039, 0.021, 0.018, 0.024). hTe comparison of pulmonary function of 3 groups at the time of 3 months atfer operation showed that there was a signiifcant difference among three groups in FVC,FVC%, FEV1, FEV1%, PEF, MVV, TLCO, TLCO% (P values were as follows: 0.019, 0.024, 0.044, 0.021, 0.037, 0.029, 0.045, 0.017).ConclusionNo matter in the early stage atfer surgery or at the time of 3 months atfer surgery, the patients’ pulmonary function in VATS segmentectomy is better than the data of VATS lobectomy group, and the pulmonary function data of VATS lobectomy patients recovered better than the open thoracotomy group.关键词
肺肿瘤/肺功能/微创手术Key words
Lung neoplasms/Pulmonary function/Minimally invasive surgery
