中国感染控制杂志2016,Vol.15Issue(10):726-729,4.DOI:10.3969/j.issn.1671-9638.2016.10.002
某部队医院官兵创伤感染的病原菌分布及耐药性
Distribution and antimicrobial resistance of pathogens causing wound in-fection in army officers and soldiers in a military hospital
摘要
Abstract
Objective To understand the distribution and antimicrobial resistance of pathogens causing wound in-fection in army officers and soldiers following military training injury,and provide reference for antimicrobial use in clinical anti-infection treatment.Methods Wound secretion from injured army patients who were admitted to a mili-tary hospital between January 2014 and June 2015 was performed bacterial culture and antimicrobial susceptibility testing.Results 647 pathogenic bacteria strains were isolated from 1 029 wound secretion specimens ,isolation rate was 62.88%,the top 6 isolated bacteria were Staphylococcus aureus (S .aureus ,29.99%,n =194),Escherichia coli (E.coli,19.32%,n=125),Pseudomonas aeruginosa (19.17%,n=124),Enterococcus spp .(13.60%,n=88), Klebsiella pneumoniae (K .pneumoniae ,7.73%,n =50),and Acinetobacter baumannii (A.baumannii,5.87%, n=38).S .aureus and Enterococcus spp .had high susceptibility to vancomycin,linezolid ,and daptomycin (resist-ance rates ≤3.41 %),44.33% of S .aureus were methicillin-resistant,2.27% of Enterococcus spp .were vancomy-cin-resistant .E.coli and K .pneumoniae had high susceptibility rates to piperacillin/ tazobactam (resistance rates were 1 .60% and 0 respectively),except A.baumannii,resistance rates of gram-negative bacteria to carbapenems were all low (resistance rates ≤4.00%).Conclusion Military clinicians should select appropriate antimicrobial agents according to antimicrobial susceptibility testing results,reduce the disability rate due to infection in trauma patients,and provide clinical support for the treatment of the wounded.关键词
创伤/感染/病原菌/耐药性/抗药性,微生物/合理用药Key words
trauma/infection/pathogen/drug resistance/drug resistance,microbial/rational antimicrobial use分类
医药卫生引用本文复制引用
徐忠玉,郭健莲,肖斌龙,刘惠娜,江先海..某部队医院官兵创伤感染的病原菌分布及耐药性[J].中国感染控制杂志,2016,15(10):726-729,4.基金项目
南京军区面上项目南京军区医学科技创新课题 ()