中国畜牧兽医2016，Vol.43Issue(10)：2621-2627,7.DOI:10.16431/j.cnki.1671-7236.2016.10.016
转lncRNA-GTL2对小鼠肠道微生物菌群组成的影响
Effects of lncRNA-GTL2 Transgenosis on Gut Microbiota Composition in Mice
摘要
Abstract
This research was aimed to study whether the lncRNA would have effects on the struc-ture and constitution of the intestinal microbial colonies in mice.High throughout sequencing was used to sequence and analyze the intestinal microbial colonies in both transgenic and non-trans-genic mice of three months old.We conducted comparison and t-test at the level of phylum and ge-nus.The result showed that transferred into long non-coding RNA genes GTL2 (lncRNA-GTL2),the mouse intestinal microbial colony structure and composition had no significant differ-ences in the overall,within the same gender,but there were individual differences.Therefore,this study didn’t find that long non-coding RNA transfered had a significant impact on the intestinal microflorain the phylum and genus level.关键词
转基因/lncRNA-GTL2/高通量测序/肠道微生物Key words
transgenic/lncRNA-GTL2/high-throughput sequencing/intestinal microorganisms分类
生物科学引用本文复制引用
范新浩,王子帅,梁国明,杨亚岚,李奎,宋德贵,唐中林..转lncRNA-GTL2对小鼠肠道微生物菌群组成的影响[J].中国畜牧兽医,2016,43(10):2621-2627,7.基金项目
国家自然科学基金(31171192)；中国农业科学院科技创新工程项目(cxgc-ias-16) （31171192）
