中国药房2016,Vol.27Issue(29):4083-4084,4085,3.DOI:10.6039/j.issn.1001-0408.2016.29.15
我院2011-2014年喹诺酮类药物致不良反应报告分析
Analysis of Quinolones-induced ADR Reports in Our Hospital from 2011 to 2014
任培培1
作者信息
- 1. 沈阳市第四人民医院药剂科,沈阳 110031
- 折叠
摘要
Abstract
OBJECTIVE:To investigate the general regularity and characteristics of ADR induced by quinolones,and to pro-vide reference for rational drug use in the clinic. METHODS:A total of 84 quinolones-induced ADR reports in our hospital from 2011 to 2014 were analyzed statistically in respects of general information,drug use,organs/systems involved in ADR,clinical manifestations,outcome and DDDs. RESULTS:The adverse reactions were caused by 7 kinds of drugs,among which 89.29% of them were caused by intravenous injections,manifesting as lesion of skin and its appendants,digestive system and nervous system injury,etc. The proportion of female patients(60.71%)was higher than that of male(39.29%). No serious ADR was found,and all patients were recovered or cured. CONCLUSIONS:Gatifloxacin injection shows the low safety. The monitoring of ADR in-duced by quinolones should be strengthened to ensure the safe and effective use of drugs.关键词
喹诺酮类药物/不良反应/用药频度/报告/分析Key words
Quinolones/Adverse drug reaction/DDDs/Report/Analysis分类
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任培培..我院2011-2014年喹诺酮类药物致不良反应报告分析[J].中国药房,2016,27(29):4083-4084,4085,3.