中国药房2016，Vol.27Issue(29)：4115-4116,4117,3.DOI:10.6039/j.issn.1001-0408.2016.29.27
瑞舒伐他汀对血脂异常的老年患者血脂及甲状腺结节的影响
Effects of Rosuvastatin on Blood Lipid and Thyroid Nodules in Elderly Patients with Dyslipidemia
王艳飞 1焦丽 1赵红玲 1薛燕 1李文秀1
作者信息
- 1. 哈励逊国际和平医院老年病二科，河北衡水 053000
- 折叠
摘要
Abstract
OBJECTIVE:To investigate the effects and safety of rosuvastatin on blood lipid and thyroid nodules in elderly pa-tients with dyslipidemia. METHODS:70 elderly patients with dyslipidemia were selected and randomly divided into control group (33 cases) and treatment group (37 cases). Control group was treated with routine treatment as abstain from tobacco and drink, low fat diet,Aspirin enteric-coated tablets 100 mg at bed time;treatment group was additionally treated with Rosuvastatin calcium tablet 10 mg at bed time,on the basis of control group. Both groups received the treatment for consecutive 12 weeks. BMI,blood lipid and the size of thyroid nodules were compared between 2 groups before and after treatment,and the occurrence of ADR was also observed. RESULTS:There was no significant difference in BMI between 2 groups before and after treatment (P>0.05). There was no significant difference in blood lipid level and the size of thyroid nodules between 2 groups before and after treatment (P>0.05). The blood lipid level and the size of thyroid nodule of 2 groups were improved significantly after treatment,and the treatment group was significantly better than the control group,with statistical significance(P<0.05). 2 pationts of creatment suf-fered from the increase of ALT but recovered withont angtreatment. CONCLUSIONS:Rosuvastatin can significantly improve blood lipid and decrease thyroid nodules in elderly patients with dyslipidemia with good safety.关键词
瑞舒伐他汀/老年患者/血脂异常/甲状腺结节Key words
Rosuvastatin/Elderly patients/Dyslipidemia/Thyroid nodules分类
医药卫生引用本文复制引用
王艳飞,焦丽,赵红玲,薛燕,李文秀..瑞舒伐他汀对血脂异常的老年患者血脂及甲状腺结节的影响[J].中国药房,2016,27(29):4115-4116,4117,3.
