中国药理学通报2016,Vol.32Issue(10):1345-1347,1348,4.DOI:10.3969/j.issn.1001-1978.2016.10.004
染料木素抗骨质疏松研究进展
Research progress of anti-osteoporotic effects of genistein
摘要
Abstract
Genistein, as one kind of phytoestrogens, can stimu-late osteoblastic proliferation, differention and mineralization, and can also inhibit bone resorption activity of osteoclast. The effect of genistein on bone metabolism lies in various molecular mechanisms. This paper reviews the research progress of the an-ti-osteoporotic action of genistein and its mechanism, which may provide a basis for the research and development of new agents to treat osteoporosis.关键词
染料木素/骨质疏松/成骨细胞/破骨细胞/植物雌激素/机制Key words
genistein/osteoporosis/osteoblast/osteoclast/phy-toestrogens/mechanism分类
医药卫生引用本文复制引用
赖文秀,杨亚军,崔燎..染料木素抗骨质疏松研究进展[J].中国药理学通报,2016,32(10):1345-1347,1348,4.基金项目
国家自然科学基金资助项目( No 81273518 ()
81673814) ()
广东省科技计划项目( No 2012B060300027, No 2016A020215148) ( No 2012B060300027, No 2016A020215148)
广东医学院科技创新基金项目(No STZF 101104) (No STZF 101104)