中国药理学通报2016，Vol.32Issue(10)：1353-1356,4.DOI:10.3969/j.issn.1001-1978.2016.10.006
牡荆素的神经保护作用及机制研究进展
Research progress on neuroprotective effects of vitexin and its mechanisms
摘要
Abstract
Vitexin, a natural flavonoid compound, has extensive pharmacological activity. In recent years, many studies have re-vealed that vitexin has significant protective effects on central nervous system and peripheral nervous system, including anti-memory impairment, anti-epilepsy, anti-ischemic hypoxic brain damage, anti-depression, analgesia, etc. Vitexin exerts neuro-protective effects through the mechanisms of multiple pathways and multi-targets, such as reducing free radical level, inhibiting neuronal apoptosis, modulating inflammatory factors and related pathways, and regulating neurotransmitters and related recep-tors. This review mainly discusses the neuroprotective effects of vitexin and its underlying mechanisms.关键词
牡荆素/神经保护作用/作用机制/镇痛/受体/综述Key words
vitexin/neuroprotection effects/mechanisms/An-algesia/Receptors/Review分类
医药卫生引用本文复制引用
毛丽娜,朱清,李俊旭..牡荆素的神经保护作用及机制研究进展[J].中国药理学通报,2016,32(10):1353-1356,4.基金项目
国家自然科学基金面上项目( No 81373390) （ No 81373390）
江苏省高校优势学科建设工程资助项目( PAPD) （ PAPD）
