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急性大脑中动脉闭塞性脑梗死静脉溶栓后血管再通与预后

廖晓凌 王伊龙 潘岳松 王春娟 陈胜云 赵性泉 王春雪 刘丽萍 王拥军

中国卒中杂志2016,Vol.11Issue(10):824-828,5.
中国卒中杂志2016,Vol.11Issue(10):824-828,5.DOI:10.3969/j.issn.1673-5765.2016.10.003

急性大脑中动脉闭塞性脑梗死静脉溶栓后血管再通与预后

The Recanalization and Prognosis of Acute Cerebral Infarction Patients with Middle Cerebral Artery Occlusion after Intravenous Thrombolytic Treatment

廖晓凌 1王伊龙 1潘岳松 1王春娟 1陈胜云 1赵性泉 1王春雪 1刘丽萍 1王拥军1

作者信息

  • 1. 100050 北京首都医科大学附属北京天坛医院神经病学中心
  • 折叠

摘要

Abstract

Objective To investigate the association between recanalization and prognosis of acute cerebral infarction patients with middle cerebral artery (MCA) occlusion after intravenous thrombolytic treatment. <br> Methods The data of acute cerebral infarction patients with MCA occlusion who received intravenous thrombolytic treatment were retrospectively analyzed. The recanalization rate after thrombolysis was analyzed. The safety and efifcacy outcome between recanalization group and no recanalization group were compared. <br> Results A total of 67 patients were included. The rate of recanalization of MCA was 55.2%. For the functional independence outcome at 90 days, recanalization group (n=37) was signiifcantly better than no recanalization group (n=30) (72.97%vs 43.33%,OR=3.5,P=0.014). For the excellent recovery outcome at 90 days, the former was also significantly better than the latter (64.86%vs 26.67%, OR=5.1,P=0.002). There were no signiifcant differences for the symptomatic intracranial hemorrhage and mortality between the two groups. <br> Conclusion The recanalization rate of acute cerebral infarction patients with MCA occlusion is relatively high, and recanalization is strongly associated with prognosis. For these patients, bridge-treatment is the optimal choice.

关键词

脑梗死/溶栓/再通/预后

Key words

Cerebral infarction/Thrombolytic treatment/Recanalization/Prognosis

引用本文复制引用

廖晓凌,王伊龙,潘岳松,王春娟,陈胜云,赵性泉,王春雪,刘丽萍,王拥军..急性大脑中动脉闭塞性脑梗死静脉溶栓后血管再通与预后[J].中国卒中杂志,2016,11(10):824-828,5.

基金项目

“十二五”及“十一五”国家科技支撑计划 ()

中国卒中杂志

OACSTPCD

1673-5765

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