中国卒中杂志2016，Vol.11Issue(10)：863-867,5.DOI:10.3969/j.issn.1673-5765.2016.10.010
原发性中枢神经系统血管炎（附8例经病理确诊病例及文献复习）
Primary Central Nervous System Vasculitis (8 Cases Report and Literature Review)
雷爱弟 1张星虎 2周衡2
作者信息
- 1. 361100 厦门厦门市第五医院神经内科
- 2. 首都医科大学附属北京天坛医院神经病学中心，神经感染与免疫科
- 折叠
摘要
Abstract
Objective To analyze and compare the diagnosis method of primary central nervous system vasculitis (PCNSV) according to the international standard. <br> Methods A total of 8 cases who were admitted to Department of Neuro-infection and Immunology of Neurological Disease Center of Beijing Tiantan Hospital, Capital Medical University during Jan.1st, 2012 to Dec.31st, 2015 and diagnosed with PCNSV were reviewed. Their clinical descriptions, laboratory examinations, neuroimaging and pathological characteristic were analyzed. <br> Results The most common clinical symptoms were: chronic headache, seizures, stroke like focal neurological deifcits, mental and behavioral abnormalities and symptoms of the external pyramidal system. No speciifc blood biochemical and cerebral spinal lfuid (CSF) abnormalities were found in all patients. Intracranial abnormal signal was seen in magnetic resonance imaging (MRI). Magnetic resonance angiography (MRA) and digital subtraction angiography (DSA) were not significantly abnormal. Brain biopsy was performed in 8 patients and the pathologic results were consistent with PCNSV expression. <br> Conclusion The diagnosis of PCNSV should consider the patient's clinical manifestations, laboratory tests and imaging findings. The extensive development of brain biopsy is helpful to improve the diagnostic rate of the disease.关键词
原发性中枢神经系统血管炎/脑组织活检Key words
Primary central nervous system vasculitis/Brain biopsy引用本文复制引用
雷爱弟,张星虎,周衡..原发性中枢神经系统血管炎（附8例经病理确诊病例及文献复习）[J].中国卒中杂志,2016,11(10):863-867,5.
