重庆医学2016，Vol.45Issue(30)：4193-4196,4.DOI:10.3969/j.issn.1671-8348.2016.30.006
定量CT 研究中老年男性椎后肌群退行性改变与年龄的相关性
Relationships between the spine muscle degenerative changes and the aging in elderly males by quantitative computed tomograph
摘要
Abstract
Objective To explore the age related decline in spine muscle volume and fat content in healthy elderly males . Methods Totally 88 males aged 50-79 years were selected from the patients who underwent quantitative CT (QCT) exam of lum‐bar spine .They were subgrouped by 50- <60 years ,60- <70 years and 70-79 years .The muscle fat area ,skeletal muscular area , muscle fat infiltration (MFI) ,abdominal visceral fat volume and subcutaneous fat volume ,abdominal total fat volume were measured by the QCT software .Statistical analysis was performed using intraclass correlation coefficient ,ANOVA with post hoc Bonferroni correction ,Pearson correlation analysis and multiple regression analysis .Results Compared to other two groups ,subjects in 70-79 years subgroup had highest muscle fat area/MFI and least skeletal muscular mass(P<0 .05) .Age‐dependent correlation was found in muscle fat mass(r=0 .381 ,P<0 .05) and MFI(r=0 .358 ,P=0 .001) ,but no obvious correlation was found between age and skeletal muscular mass .Age was the only factor entered into the all three paravertebral muscle composition regression equations , meaning age may had an important influence on paravertebral muscle degeneration .Conclusion Lumbar paravertebral muscle de‐generation in elderly men is correlated with the aging and MFI ,which may play a important role in the normative age‐related decline of skeletal muscle .关键词
椎后肌群/退行性变/脂肪浸润/定量CTKey words
vertebral muscle/degeneration/muscle fat infiltration/quantitative CT分类
医药卫生引用本文复制引用
蔡韦,程晓光,王玲,陈颐中,焦顺霞,赵茜,李新彤,端木羊羊,王晨,侯雪..定量CT 研究中老年男性椎后肌群退行性改变与年龄的相关性[J].重庆医学,2016,45(30):4193-4196,4.基金项目
国家自然科学基金资助项目（81401407）；北京市卫计委首都医学发展科研基金资助项目（首发2014-2-1122）；北京市卫生局“215”高层次卫生技术人才培养计划基金资助项目（2009-2-03）。 （）
