湖南中医药大学学报2016，Vol.36Issue(10)：91-95,5.DOI:10.3969/j.issn.1674-070X.2016.10.023
健脾益肾法治疗化疗后白细胞减少症的Meta分析
Meta Analysis of Spleen-invigorating and Kidney-tonifying Method in the Treatment of Leukopenia after Tumor Chemotherapy
李成银 1易宗毕 2李俊娇 3赵井苓 3王琦苑1
作者信息
- 1. 湖北省中医院，湖北 武汉 430061
- 2. 中国医学科学院北京协和医学院肿瘤医院，北京100021
- 3. 湖北中医药大学，湖北 武汉 430065
- 折叠
摘要
Abstract
Objective To evaluate effectiveness and safety of spleen-invigorating and kindney-tonifying method in the treatment of leukopenia after tumor chemotherapy. Methods The papers on spleen-invigorating and kindney-tonifying method in the treatment of leukopenia after tumor chemotherapy, published in databases of VIP, CNKI, SinoMed, WANGFANG DATA, Web of Science, EMBASE from January 2000 to May 2016, were searched and Meta analysis was performed on the data by revman 5.2 software and stata11. Results Totally 24 RCT involving 2369 cases were included.The meta analysis results showed that the total effectiveness (RR=1.28,95%CI[1.18,1.39], Z=5.73, P<0.001) and significant effectiveness (RR=1.65, 95%CI [1.36,1.99], Z=5.11,P<0.001) by spleen-invigorating and kindney-tonifying method were higher than that with nomal oral drugs for rising leukocyte in the treatment of leukopenia after tumor chemotherapy. Conclusion The spleen-invigorating and kindney-tonifying method in the treatment of leukopenia after tumor chemotherapy is superior to normal oral drugs in effectiveness. However, the above conclusion should be further confirmed by conducting more large-scale and well-designed RCTs due to the limited quantity and quality of the included studies.关键词
白细胞减少症/中医药疗法/健脾益肾/化疗/Meta分析Key words
leukopenia/therapy of traditional Chinese medicine/spleen-invigorating and kidney-tonifying/chemotherapy/Meta analysis分类
医药卫生引用本文复制引用
李成银,易宗毕,李俊娇,赵井苓,王琦苑..健脾益肾法治疗化疗后白细胞减少症的Meta分析[J].湖南中医药大学学报,2016,36(10):91-95,5.
