湖南中医药大学学报2016，Vol.36Issue(10)：96-99,4.DOI:10.3969/j.issn.1674-070X.2016.10.024
中药复方防治脑梗死机制研究进展
Research Progress of the Mechanism of Chinese Herbal Compound in Treatment of Cerebral Infarction
摘要
Abstract
Cerebral infarction is a common clinical and multiple ischemic cerebrovascular disease, which treatment methods of modern medicine are mainly including early thrombolytic therapy, nerve cell protection therapy, interventional therapy, surgical therapy and so on. Eventhough recent therapeutic efficacy of theses methods is significant, their clinical application is limited due to the unavoided side effects and strict treatment access conditions. Chinese medicine has an indispensable advantage in treatment of cerebral infarction for the concept of wholism of diagnosis and syndrome differentiation. Chinese herbal formulation has multi-targets, multi-link, multi-way and network overall adjustment advantage. In this article, we will systematically review the principle of action of Chinese herbal formulation in treatment with cerebral infarction from anti-oxidative damage, inhibition of ecitability amino acid and overload of calcium, inhibition of apoptotic cell activation and promotion of vessel endothelial growth factor nerve regeneration. That is to provide the scientific evidence for prevention and treatment of ischemic cerebrovascular disease by Chinese medicine.关键词
脑梗死/中药复方/抗氧化损伤/抑制兴奋氨基酸与钙超载/凋亡细胞/血管内皮生长/神经再生功能Key words
cerebral infarction/Chinese herbal compound/mechanism of action/anti-oxidative damage/inhibition of ecitability amino acid and overload of calcium/inhibition of apoptotic cell activation/promote vessel endothelial growth factor/nerve regeneration分类
医药卫生引用本文复制引用
季梦漂,李鑫,周德生,李杰,吴涛,李琳,胡志希..中药复方防治脑梗死机制研究进展[J].湖南中医药大学学报,2016,36(10):96-99,4.基金项目
国家自然科学基金资助项目（81373550，81202647）。 （）
