实用医学杂志2016，Vol.32Issue(17)：2833-2836,4.DOI:10.3969/j.issn.1006-5725.2016.17.015
外伤性枯草杆菌性眼内炎临床分析
摘要
Abstract
Objective To study the clinical features and investigate the early diagnosis and treatment of traumatic endophthalmitis caused by bacillus subtilis. Methods In this study, the clinical and laboratory data of twenty-two cases (22 eyes) with traumatic endophthalmitis caused by bacillus subtilis treated at Zhongshan Ophthalmic Center, Sun Yat-sen University between January, 2003 and December, 2013 have been summarized. Results In these 22 cases, 15 cases were combined with intraocular foreign bodies, 15 cases with corneal infiltration and 7 cases with orbital cellulitis. The surgical procedures of the patients included wound suture and intraocular injection of antibiotics ( 7 cases ) , vitrectomy alone ( 15 cases ) and vitrectomy with silicone oil tamponade (8 cases). The outcome of treatment was 11 cases without light perception, 11 cases with light perception to 0.05 and 3 cases with evisceration. The bacillus subtilis strains of these 22 cases were sensitive to tobramycin , gentamycin, cefoperazone, levofloxacin and ofloxacin. Age, corneal infiltration and intraocular foreign bodies were the risk factors affecting prognosis (P < 0.05) of traumatic endophthalmitis while silicone oil tamponade was confirmed to be the protecting factor (P < 0.05). Conclusions Sanguinopurulent anterior chamber effusion and ring infiltration surrounding the cornea wounds are the typical signs of traumatic endophthalmitis caused by bacillus subtilis. Gentamycin, tobramycin, cefoperazone, levofloxacin and ofloxacin are effective antibiotics against bacillus subtilis. Once the diagnosis is made, vitrectomy combined with silicone oil tamponade is an optimal treatment to save visual acuity, which should be done as soon as possible.关键词
外伤性眼内炎/枯草杆菌Key words
Bacillus subtilis/Traumatic endophthalmitis引用本文复制引用
罗益文,黄文彬,李娉,陈凯佳,林晓峰..外伤性枯草杆菌性眼内炎临床分析[J].实用医学杂志,2016,32(17):2833-2836,4.基金项目
国家自然科学基金项目 （）
