实用医学杂志2016，Vol.32Issue(18)：2948-2951,4.DOI:10.3969/j.issn.1006-5725.2016.18.002
脑梗死患者99mTc－ECD SPECT／CT感兴趣区成像局部脑血流的特征
Effect of local mild hypothermia on regional cerebral blood flow in patients with cerebral infarction assessed by 99mTc-ECD SPECT imaging
摘要
Abstract
Objective To investigate the frequency of lesions detection in patients with cerebral infarction (CI) with SPECT/CT. To investigate fluctuation of regional cerebral blood flow (rCBF) and its relationship with clinical symptoms. Methods Sixty-seven CI patients without cerebellar lesion were randomly selected. The rCBF in the regions of interest (ROI) was examined by SPECT/CT, which was collected from the frontal lobe, temporal lobe, parietal lobe, occipital lobe, thalamus, basal ganglia and cerebellum. The rCBF index was calculated. The association between fluctuation of rCBF index and clinical symptoms of patients was explored. Results There were 251 positive regions in all viewing regions , the total positive rate was 31.2%. The left side was 38.1%, while the right side was 24.4% (χ²=17.522,P < 0.01). In normal group, there were no statistical difference of average rCBF between two halves (P > 0.05). However, the average rCBF on the left parietal lobe was lower (P < 0.01). The average rCBF in the abnormal group was lower than that in ipsilateral normal group (P < 0.01). The average rCBF index in the abnormal group was higher (P < 0.01). In normal group , the average rCBF on the frontal lobe and parietal lobe was low , but the average rCBF on the thalamus and basal ganglia was high (P < 0.01). In abnormal group, there were no statistical difference in the average rCBF (P >0.05). rCBF≥0.7 is a clinical sign of abnormal ROI. Conclusion 30% of ROI of CI patients have lesions and the positive rate of the left side was higher. The biological rCBF values of all lobes were different. Therefore, rCBF index could be used to reflect whether the ROI is normal. rCBF≥0.7 could be used as a sign to quantitatively assess abnormal ROI in clinical practice.关键词
腔隙性脑梗死/SPECT/CT/脑血流灌注显像/局部脑血流Key words
Infarction/SPECT/CT/Cerebral blood flow perfusion imaging/Regional cerebral blood flow引用本文复制引用
罗章伟,李天资,李雪斌,黄俊芳,蒙兰青,李清锋,梁烨,李近都..脑梗死患者99mTc－ECD SPECT／CT感兴趣区成像局部脑血流的特征[J].实用医学杂志,2016,32(18):2948-2951,4.基金项目
国家自然科学基金项目（编号81160146）；广西卫生厅资助项目 （）
