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脑死亡与心死亡后器官捐献成人供受者单肾移植效果比较

黄焕文 刘丁 胡建敏 陈桦 李民 李留洋 郭颖 赵明

实用医学杂志2016,Vol.32Issue(18):3011-3014,4.
实用医学杂志2016,Vol.32Issue(18):3011-3014,4.DOI:10.3969/j.issn.1006-5725.2016.18.019

脑死亡与心死亡后器官捐献成人供受者单肾移植效果比较

Comparison the outcome of donation after brain death and cardiac death for adult-to-adult single kidney transplantation

黄焕文 1刘丁 1胡建敏 1陈桦 1李民 1李留洋 1郭颖 1赵明1

作者信息

  • 1. 510280 广州市,南方医科大学珠江医院器官移植科
  • 折叠

摘要

Abstract

Objective To compare the outcome of adult-to-adult single kidney transplantation from donation after drain death and cardiac death. Methods The outcome of adult-to-adult single kidney transplantation from October 2012 to September 2015 in kidney transplantation center of Zhujiang Hospital was retrospectively analyzed. 53 recipients received donation from donors after brain death (DBD group) and 28 from cardiac death (DCD group). The deadline of follow-up is May 2016. Results During the period of observation, the mean follow-up was (17.26±10.85) months and patient's survival rate was 100%. When compared graft survival rate with the two groups, survival rate is 93.7% in DBD group and 92% in DCD group (χ²= 0.184,P = 0.668). There was no statistically significant difference (P > 0.05), the overall incidence of DGF was 28.4%. General DGF incidence is 28.4%, and DGF incidence between groups is χ²= 4.402,P = 0.036. Infection rate within 1 year is χ²= 4.507,P = 0.034, and the difference is significant (P < 0.05). There were no statistically significant difference (P > 0.05) in AR, eGFR of 1 month, proteinuria of 1 month after, transplantation and surgical complications. Conclusions Adult-to-adult single kidney transplantation from donation after cardiac death (DCD) has a higher rate of incidence of DGF, and the postoperative infection rate within 1 year. Renal transplantation from donation after cardiac death could have a good outcome.

关键词

脑死亡/心死亡/肾移植/临床疗效

Key words

Donation after brain death/Donation after cardiac death/Kidney transplant/Clinical effect

引用本文复制引用

黄焕文,刘丁,胡建敏,陈桦,李民,李留洋,郭颖,赵明..脑死亡与心死亡后器官捐献成人供受者单肾移植效果比较[J].实用医学杂志,2016,32(18):3011-3014,4.

基金项目

国家自然科学基金资助项目 ()

实用医学杂志

OA北大核心CSTPCD

1006-5725

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