实用医学杂志2016，Vol.32Issue(18)：3026-3029,4.DOI:10.3969/j.issn.1006-5725.2016.18.023
ATRX在不同类型中枢神经系统肿瘤中的表达及其在鉴别诊断中的意义
Expression of ATRX in different central nervous system tumors and the usefulness in differential diagnosis
摘要
Abstract
Objective To investigate the expression of α-thalassemia/mental retardation syndrome X-linked (ATRX) in different central nervous system tumors and the meaningness in differential diagnosis. Methods Expression of ATRX protein was determined by immunohistochemistry in astrocytomas , oligodendrogliomas, glioblastomas, ependymomas and meningiomas. Results Positive expression levels of ATRX in astrocytomas were significantly lower than those in oligodendrogliomas,glioblastomas, ependymomas and meningiomas (all P <0.01). Conclusion The loss of ATRX was mainly occurred in astrocytomas, which could be as a astrocytoma marker in diagnosis.关键词
中枢神经系统肿瘤/ATRXKey words
Central nervous system tumors/ATRX引用本文复制引用
褚明亮,张著学,张赟,杨迎春,沈和德,易韦..ATRX在不同类型中枢神经系统肿瘤中的表达及其在鉴别诊断中的意义[J].实用医学杂志,2016,32(18):3026-3029,4.基金项目
贵州省科学技术基金项目（编号黔科合J字［2015］2086号）；贵州省科技厅项目 （）
